Colchicine interferes with cell division because of

Splitting of chromosomes

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Non-pairing of chromosomes

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Double replication of chromosomes

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Non-formation of spindle

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Solution

The correct option is D Non-formation of spindle
The answer is "Non-formation of spindle" i.e. option D
Colchicine is an inhibitor of microtubule growth, assembly, and polymerization. During cell division, if colchicine is present it would block the spindle formation by disturbing microtubule assembly and growth.

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