Colchicine is a drug known to stop the formation of spindle fibres. what will happen to when dividing cells in a cell culture are treated with colchicines

Cells will die

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Cells will not enter into cell cycle

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Cells will enter into cell cycle but get arrested in metaphase

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Cells will complete the cell cycle

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Solution

The correct option is C Cells will enter into cell cycle but get arrested in metaphase
Since colchicines inhibits growth of spindle fibres and the major role of spindle fibre is to pull the chromosomes to the poles during anaphase. So, colchicines treated cells will enter in cell cycle but will be arrested at metaphase.

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Colchicine is a drug known to stop the formation of spindle fibres. what will happen to when dividing cells in a cell culture are treated with colchicines

Q. If cells in process of dividing are subjected to colchicine, a drug that interferes with the functioning of the spindle apparatus, at which stage will mitosis be arrested?

Q. Chromosomes in metaphase get arranged at the equatorial plate (see Fig. 1). When these cells are treated with colchicine, cell division is arrested and the cells never enter anaphase. If we were to compare a colchicine treated cell at metaphase and an untreated cell in the same phase, we notice that chromosomes are more dispersed and do not arrange themselves on the equatorial plate in the treated cells (see Fig 2.).
Using this information, which of the following will be affected by colchicine?

Q. Colchicine which prevents spindle formation is chemically a/an

Q. A dividing diploid cell supplied with colchicine will become

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