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Question

Combination of haemoglobin with CO2 in lungs can be promoted by

A
Increasing CO2 concentration in blood
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B
Increasing O2 concentration in blood
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C
Decreasing O2 concentration in blood
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D
None of the above
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Solution

The correct option is B Decreasing O2 concentration in blood
Carbon dioxide is transported to the lungs either dissolved in plasma (5%), bound to proteins and haemoglobin in particular (10%) or combines with water as carbonic acid (85%). While haemoglobin can easily carry O2 in it, while transporting CO2, it forms the compound carbaminohemoglobin which lowers the haemoglobin's affinity for oxygen. The combination of CO2 with haemoglobin in the lungs can thus be promoted by Haldane effect as deoxygenation (decreasing of oxygen) of the blood increases its ability to carry carbon dioxide.
Therefore, the correct answer is option C.

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