Question

Consider the following four statement (i-iv) regarding kidney transplant and select the correct statements
(i) Even if a kidney transplant is proper the recipient may need to take immuno-suppressants for a long time.
(ii) The cell-mediated immune response is responsible for the graft rejection.
(iii) The B-lymphocytes are responsible for rejection of the graft.
(iv) The acceptance or rejection of a kidney transplant depends on specific interferons.

The correct statements are

• A. (ii) and (iii)
• B. (iii) and (iv)
• C. (i) and (iii)
• D. (i) and (ii)

Answer 1

The correct option is D (i) and (ii)

D. (i) and (ii)

Reason: A kidney transplant from an identical twin, called isograft. If kidney is transplanted from other person except twin is called allograft. As no two individuals have same HLA alleles or MHC proteins, except identical twins the person requires immunosuppressant drug like cyclosporin throughout his life. The cell-mediated immune response, the T-cell mediated immunity is responsible for graft rejection and not B-lymphocytes.