Question

Consider the following four-statements(a-d) regarding kidney transplant and select the two correct ones out of these.
(a)Even if a kidney transplant is proper the recipient may need to take immunosuppressants for a long time.
(b)The cell-mediated immune response is responsible for the graft rejection
(c)The B- lymphocytes are responsible for rejection of the graft
(d)The acceptance or rejection of a kidney transplant depends on specific interferons .
The two correct statements are

• A. (c) and (d)
• B. (a) and (c)
• C. (a) and (b)
• D. (b) and (c)

Answer 1

Answer: (C)

(a) and (b)

A kidney transplant is allograft. As no two individuals have same HLA alleles or MHC proteins, except identical twins the person requires immunosuppressant drug like cyclosporin throughout his life.

The cell-mediated immune response, i.e., the T-cell mediated immunity is responsible for graft rejection and not B-lymphocytes. Hence, option C is correct.