Question

Cri-du-chat is?

• A. Gene disorder
• B. Allosomal disorder
• C. X-chromosomal disorder
• D. Autosomal disorder

Answer 1

The correct option is D

Explanation of the correct option:

1. A disease caused by a gene located on a chromosome other than a sex chromosome (autosomal chromosome) is called autosomal disorder.
2. Cri-du-chat (cat's cry) syndrome, also known as 5p- (5p minus) syndrome, is a chromosomal condition that results when a piece of chromosome 5 (autosomal chromosome) is missing.
3. Children with this disease have a small head with unusual facial features, severe mental retardation and make a sound like a cat while crying.
4. The larynx develops abnormally due to the chromosome deletion, which affects the sound of the child’s cry.

Explanation of the incorrect answers:

Option A:

1. The disorders caused by the genetic abnormality or abnormality in the DNA.
2. Four of the main types are- Single-gene inheritance diseases, multifactorial genetic inheritance disorders, chromosome abnormalities and mitochondrial genetic inheritance disorders.

Option B:

1. An allosome is a sex chromosome that differs in size, form and behaviour from an autosome.
2. Humans have one pair of allosomes These chromosomes contain genes that determine the biological sex of an organism.
3. Abnormalities in the sex chromosomes causes the allosomal disorders.

Option C:

1. The disorder in the X chromosome are X-chromosomal disorders.
2. This is also known as allosomal disorder.

Final answer: Cri-du-chat is autosomal disorder.