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Question

Define glomerular filtration?


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Solution

Glomerular filtration:

  1. Waste is excreted from the human body, mainly in form of urine.
  2. Our kidneys generally play a major role in the process of excretion.
  3. Constituents of normal human urine include 95 percent water and 5 percent solid wastes.
  4. Glomeruli are little filters found in our kidneys.
  5. These filters aid in clearing the blood of waste and extra fluid.
  6. Glomerular filtration seems to occur in the glomerulus where blood is filtered.
  7. The process occurs across the 3 layers- the epithelium of Bowman’s capsule, the endothelium of glomerular blood vessels, & a membrane between these two layers.
  8. Blood is generally filtered in such a way that all constituents of the plasma reach the Bowman’s capsule, except the proteins. This process is referred to as ultrafiltration.
  9. Glomerular Filtration Rate or GFR is the rate at which the kidneys form the filtrate in a minute.
  10. For a healthy individual, the GFR is about 180 L/day, that is 125 ml in a minute.
  11. The Glomerular filtrate contains various organic and inorganic molecules like glucose, amino acids, ketone bodies, sodium, potassium, etc.


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