Question

Define the following as related to proteins :
(i) Peptide linkage
(ii) Primary structure
(iii) Denaturation

Answer 1

I) Peptide linkage is the peptide bond formed between the amino acids. It is a covalent bond formed between amino group of one molecule and carboxylic acid group of another molecule.

II)The primary structure of a peptide or protein is the linear sequence of its amino acid structural units. The primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end.

(III) The process in which proteins or nucleic acids lose the quaternary structure, tertiary structure and secondary structure which is present in their native state known as denaturation. by application of some external stress or compound such as a strong acid or base, a concentrated inorganic salt, an organic sol.