Juvenile hormones are secreted by a pair of endocrine glands behind the brain called the corpora allata. JHs are also important for the production of eggs in female insects.
The primary control of juvenile hormone is by:
1) the stimulation of the corpora allata by allatotropins short peptides which bind to G-protein coupled receptors, which signal the glands to produce JH, and 2), the inhibition of JH production by allatostatins.
Secondary control of the JH titre found in the hemolymph of the developing insect is metabolic inactivation of JH by JH-specific esterase and juvenile hormone epoxide hydrolase.