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Question

DNA fragments generated by the restriction endonucleases in a chemical reaction can be separated by .

A
gel electrophoresis
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B
PCR
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C
centrifugation
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D
restriction mapping
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Solution

The correct option is A gel electrophoresis
Gel electrophoresis is a technique for the analysis and separation of colloids, based on the movement of charged colloidal particles in an electrical field. DNA being a negatively charged particle moves towards anode and at anode, DNA is separated. Different sized fragments of DNA migrate at different rates, so the sample of DNA mixture get separated into different zones.

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