Yes,
In humans Some receptors can detect several different stimuli but they are usually specialised to detect one type of stimulus: light - photoreceptors in the eye. sound - vibration receptors in the ears. touch, pressure, pain and temperature - different receptors in the skin.
In animals A stimulus is a change in the environment of an organism. Animals respond to astimulus in order to keep themselves in favourable conditions. Examples of this include: Moving to somewhere warmer if they are too cold.