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Drugs interact with the active sites on enzyme and accelerate the catalytic activity of the enzyme.
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Drugs interact with the active sites on enzyme and inhibits the catalytic activity of the enzyme. A drug molecule with a structure that closely resembles that of the substrate, intermediate, or product of a particular enzymatic reaction is able to enter and bind (through noncovalent interactions) to the enzyme's active site. This 'imposter' molecule, as long as it stays in the active site, will prevent the real substrate from entering and therefore will prevent the enzyme from catalyzing its reaction.

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