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Question

During cell division the process that causes failure of separation of sister chromatids is called

A
Coincidence
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B
Interference
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C
Non-disjunction
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D
Complementation
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Solution

The correct option is C Non-disjunction
  • Nondisjunction is the failure of paired chromosomes or sister chromatids attached at the centromere to separate during cell division.
  • This results in both the parent chromosomes going into a particular daughter cell while the other daughter cell is devoid of the parent chromosomes.
  • Nondisjunction causes errors in chromosome number and results in aneuploidy.
  • For example, trisomy 21 (Down syndrome) and monosomy X (Turner syndrome).
  • It is also a common cause of early spontaneous abortions.
Thus, the correct answer is option C.

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