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Standard IX
Biology
Down's Syndrome
During cell d...
Question
During cell division the process that causes failure of separation of sister chromatids is called
A
Coincidence
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B
Interference
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C
Non-disjunction
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D
Complementation
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Solution
The correct option is
C
Non-disjunction
Nondisjunction is the failure of paired chromosomes or sister chromatids attached at the centromere to separate during cell division.
This results in both the parent chromosomes going into a particular daughter cell while the other daughter cell is devoid of the parent chromosomes.
Nondisjunction causes errors in chromosome number and results in aneuploidy.
For example, trisomy 21 (Down syndrome) and monosomy X (Turner syndrome).
It is also a common cause of early spontaneous abortions.
Thus, the correct answer is option C.
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