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Question

During cellular respiration, pyruvate undergoes oxidative decarboxylation in

A
cytoplasm
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B
mitochondrial matrix
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C
inner mitochondrial membrane
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D
outer mitochondrial membrane
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Solution

The correct option is B mitochondrial matrix
Pyruvate formed in glycolysis undergoes oxidative decarboxylation in the mitochondrial matrix. It is a complex set of reactions catalysed by pyruvate dehydrogenase enzyme. Oxidative decarboxylation of pyruvate results in the formation of acetyl CoA which starts Krebs cycle.

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