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Question

During conversion of pyruvic acid into acetyl Co-A, the pyruvic acid is

A
Oxidised.
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B
Reduced.
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C
Isomerised.
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D
Condensed.
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Solution

The correct option is A Oxidised.
The pyruvic acid formed after glycolysis may be completely oxidised into carbon dioxide and water as in aerobic respiration or may be incompletely broken down into ethyl alcohol or lactic acid during fermentation process. For the process of aerobic respiration first pyruvic acid is oxidatively decarboxylated to yield Acetyl CoA. As pyruvic acid is a three carbon atom containing molecule and acetyl CoA is a two carbon atom containing molecule, when one molecule of pyruvic acid is converted to one molecule of acetyl CoA, one molecule of carbon dioxide is released. Hence, it is a decarboxylation reaction. In this reaction one unit of reduced coenzyme NADH2 is simultaneously synthesized.
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