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B
Na+ gets inside through ion channels
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C
Na+ gets outside through ion channels
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D
All the above
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Solution
The correct option is B Na+ gets inside through ion channels The depolarization, also called the rising phase, is caused when positively charged sodium ions (Na+) suddenly rush through open voltage-gated sodium channels into a neuron. As additional sodium rushes in, the membrane potential actually reverses its polarity.