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Question

During fertilization, zona pellucida is dissolved by

A
Hyaluronidase
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B
Hyaluronic acid
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C
Renin
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D
Acrosin
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Solution

The correct option is B Acrosin
When the sperm reaches the ovum, a series of events called 'acrosomal reaction' take place. The sperm is said to release hyaluronidase from the acrosome which helps it to penetrate the corona radiata. This digets the cumulus cells surrounding the oocyte and exposes acrosin which is attached to the inner membrane of the sperm. Acrosin is mainly responsible for the dissolution of the zona pellucida, which helps in the fusion of the membranes of the sperm and egg. So, the correct answer is 'Acrosin'.

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