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Question
During transcription, the RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle-like structure. What is its DNA-binding sequence?
During transcription, the RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle-like structure. What is its DNA-binding sequence?
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Solution
The correct option is C TATA
The TATA box is present in the eukaryotic promotor region. It has a resemblance with the Pribnow box of prokaryotes. The TATA box was identified by David Hogness, and so it is also called the Hogness box. It is a 7 bp long region located 25 bp upstream to the start point. During the process of transcription the RNA polymerase binds to the TATA box, due to which the DNA assumes a saddle-like structure at this place.
The TATA box is present in the eukaryotic promotor region. It has a resemblance with the Pribnow box of prokaryotes. The TATA box was identified by David Hogness, and so it is also called the Hogness box. It is a 7 bp long region located 25 bp upstream to the start point. During the process of transcription the RNA polymerase binds to the TATA box, due to which the DNA assumes a saddle-like structure at this place.
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