The correct option is D All of the above
Nicotine is a potent parasympathomimetic alkaloid and a stimulant drug. In particular, it is both a stimulant and a relaxant. It causes a release of glucose from the liver and adrenaline from the adrenal medulla thereby causing stimulation of nerve impulses and muscle relaxation.
Nicotine also produces adverse fetal effects. It is likely that hypoxia, undernourishment of the fetus and direct vasoconstrictor effects on the placental and umbilical vessels play a role.
Therefore, the correct answer is option D.