Question

Enzyme responsible for replication of HIV in macrophages is

• A. RNA polymerase
• B. DNA ligase
• C. DNA polymerase
• D. Reverse transcriptase

Answer 1

The correct option is D Reverse transcriptase

Once inside a CD${}_4$ cell ( helper T cell ), HIV releases and uses reverse transcriptase to convert its genetic material—HIV RNA—into HIV DNA. The conversion of HIV RNA to HIV DNA allows HIV to enter the CD${}_4$ cell nucleus and combine with the cell’s genetic material—cell DNA.

So, the correct answer is 'Reverse transcriptase'