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Question

Enzyme responsible for replication of HIV in macrophages is 


A
RNA polymerase
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B
DNA ligase
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C
DNA polymerase
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D
Reverse transcriptase
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Solution

The correct option is D Reverse transcriptase
Once inside a CD$$_4$$ cell ( helper T cell ), HIV releases and uses reverse transcriptase  to convert its genetic material—HIV RNA—into HIV DNA. The conversion of HIV RNA to HIV DNA allows HIV to enter the CD$$_4$$ cell nucleus and combine with the cell’s genetic material—cell DNA.
So, the correct answer is 'Reverse transcriptase'

Zoology

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