Central Dogma

Q. Correct sequence of code transfer during polypeptide formation is

1. DNA, mRNA, tRNA and amino acids
2. DNA, tRNA, rRNA and mRNA
3. mRNA, tRNA, DNA and amino acids
4. rRNA, DNA, mRNA and tRNA

Q. Information flow or central dogma of molecular biology is

1. RNA $\to$ Proteins $\to$ DNA
2. proteins $\to$ RNA $\to$ DNA
3. RNA $\to$ DNA $\to$ Proteins
4. DNA $\to$ RNA $\to$ Proteins

Q. Which of the following summarises the cental dogma of molecular biology in humans?

1. DNA transcribed to proteins and proteins translated into RNA.
2. RNA transcribed to DNA and DNA translated into proteins.
3. DNA transcribed to RNA and RNA translated into proteins.
4. Protein transcribed to DNA and translated into RNA

Q. In a eukaryotic cell, tanscription occurs in the , and translation occurs in the .

1. nucleus
2. mitochondria
3. chloroplast
4. cytoplasm

Q. Protein is a polypeptide of amino acids.

1. True
2. False

Q. The diagram represents the 'central dogma' of molecular biology. choose the correct combination of labelling.

1. A-DNA, B- RNA, C-Protein, D-Transcription, E- Translation
2. A-Transcription, B- Translation, C-Translation, D-DNA, E- RNA
3. A-DNA, B- RNA, C-Protein, D-Translation, E- Transcription
4. A-Protein, B-RNA, C-DNA, D-Translation, E- Transcription
5. A-RNA, B- DNA, C-Protein, D-Transcription, E- Translation

Q. Central dogma of genetic information was modified by the discovery of

1. Reverse transcriptase
2. RNA polymerase
3. Ligase
4. DNA polymerase

Q. Which one of the following does not follow the central dogma of molecular biology?

1. Pea
2. HIV
3. Mucor
4. Chlamydomonas

Q. The diagram shows an important concept in the genetic implication of DNA. Fill in the blanks A to C.
$DNA\stackrel{A}{\to }mRNA\stackrel{B}{\to }protein$
This was proposed by C.

1. A-transcription B-replication C-James Watson
2. A-translation B-transcription C-Erevin Chargaff
3. A-transcription B-translation C-Francis Crick
4. A-translation B-extension C-Rosalind Franklin

Q. Select the options which will result in expression of a human gene into functional proteins.
I. cDNA for the protein is inserted into the genome of an E. coli host.
II. mRNA is inserted into the genome of an E. coli host.
III. Gene is inserted into the genome of Saccharomyces.
IV. Gene is inserted into the genome of E. coli host.

1. II and III
2. I and II
3. I and III
4. Only III