Examination of the blood of a person suspected of having anaemia shows large, immature, nucleated erythrocytes without haemoglobin. Supplementing his diet with which of the following is likely to alleviate his symptoms?
A
Thiamine
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B
Folic acid and cobalamine
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C
Riboflavin
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D
Iron compounds
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Solution
The correct option is C Folic acid and cobalamine
Anaemia is not a disease. It is a symptom of various diseases which may result from excessive blood loss, excessive blood cell destruction, or decreased blood cell formation.
Folic acid is a part of coenzymes for protein and nucleic acid metabolism and is essential for growth and formation of RBCs Its deficiency leads to anaemia failure of RBCs to mature and sprue.
Vitamin B|2or cyanocobalamin acts as a coenzyme for nucleic acid metabolism and is essential for the formation of RBCs and myelin formation. Its deficiency leads to Pernicious (injurious) anaemia and malformation of RBCs.