Centrifugation is defined as the process of separating the components of a mixture by continuously agitating the mixture at a very high speed. It utilizes the centrifugal force, generated by spinning a device manually or by a spinning motor, to separate molecules by size or density. The principle is that the denser particles are forced to the bottom and the lighter particles stay at the top when spun rapidly.
for e.g butter and cream are separated from milk by centrifugation.