Neurons, like other cells, have a cell body (called the
soma). The nucleus of the neuron is found in the soma. Neurons need to produce a lot of proteins, and most neuronal proteins are synthesized in the soma as well.
Various
processes (appendages or protrusions) extend from the cell body. These include many short, branching processes, known as
dendrites, and a separate process that is typically longer than the dendrites, known as the
axon. Dendrites
The first two neuronal functions, receiving and processing incoming information, generally take place in the dendrites and cell body. Incoming signals can be either
excitatory – which means they tend to make the neuron
fire(generate an electrical impulse) – or
inhibitory – which means that they tend to keep the neuron from firing.
Most neurons receive many input signals throughout their dendritic trees. A single neuron may have more than one set of dendrites, and may receive many thousands of input signals. Whether or not a neuron is excited into firing an impulse depends on the sum of all of the excitatory and inhibitory signals it receives. If the neuron does end up firing, the nerve impulse, or
action potential, is conducted down the axon. Axons
Axons differ from dendrites in several ways.
- The dendrites tend to taper and are often covered with little bumps called spines. In contrast, the axon tends to stay the same diameter for most of its length and doesn't have spines.
- The axon arises from the cell body at a specialized area called the axon hillock. In motor neurons and interneurons, it's at the axon hillock that the action potential is initiated.
- Finally, many axons are covered with a special insulating substance called myelin, which helps them convey the nerve impulse rapidly. Myelin is never found on dendrites.
Towards its end, the axon splits up into many branches and develops bulbous swellings known as
axon terminals (or
nerve terminals). These axon terminals make connections on target cells. Synapses
Neuron-to-neuron connections are made onto the dendrites and cell bodies of other neurons. These connections, known as
synapses, are the sites at which information is carried from the first neuron, the
presynaptic neuron, to the target neuron (the
postsynaptic neuron). The synaptic connections between neurons and skeletal muscle cells are generally called neuromuscular junctions, and the connections between neurons and smooth muscle cells or glands are known as neuroeffector junctions.
At most synapses and junctions, information is transmitted in the form of chemical messengers called
neurotransmitters. When an action potential travels down an axon and reaches the axon terminal, it triggers the release of neurotransmitter from the presynaptic cell. Neurotransmitter molecules cross the synapse and bind to membrane receptors on the postsynaptic cell, conveying an excitatory or inhibitory signal.
Thus, the third basic neuronal function – communicating information to target cells – is carried out by the axon and the axon terminals. Just as a single neuron may receive inputs from many presynaptic neurons, it may also make synaptic connections on numerous postsynaptic neurons via different axon terminals.