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Question

Feulgen test is unique for DNA which is

A
Gentian violet
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B
Neutral red
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C
Basic fuchsin
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D
Cotton blue
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Solution

The correct option is C Basic fuchsin
Basic dyes stain chromosomes and other nuclear structures. Examples of such dyes are Basic fuchsin, Crystal Violet, Methyl Green, Safranin. Feulgen or Schiff's Reagent was developed by Feulgen and Rossenbeck in 1924. It employs basic fuchsin after acid hydrolysis. The reaction is specific for DNA. Acid hydrolase separates purines and exposes aldehyde groups of deoxyribose sugar which react with Schiff's reagent to produce the stain.
So, the correct answer is 'Basic fuchsin'.

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