Figure given below depict the procedure for gene therapy. Pick up the disorders for which this technique has been applied successfully.
A
Adenosine Deaminase (ADA) Deficiency
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B
AIDS
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C
Myasthenia gravis
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D
Both (a) and (C)
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Solution
The correct option is A Adenosine Deaminase (ADA) Deficiency ADA deficiency or adenosine deaminase deficiency is a genetic disorder.
Gene therapy is the transfer of the normal gene into body cells to correct a genetic defect. It can be used to treat genetic diseases like severe combined immunodeficiency. SCID is caused by a defect in the gene for the enzyme adenosine deaminase (ADA).
These patients have non-functioning T lymphocytes and the patients are treated with injections of their white blood cells that have been engineered to carry the normal ADA alleles.
So, the correct option is 'Adenosine Deaminase (ADA) Deficiency'