Question

Find out the name of the microbes from which Cyclosporin A(an immunosuppressive drug) and Statins (blood chloestrol lowering agents) are obtained.

Answer 1

Cyclosporin A, a fungal product (Trichoderma polysporum), is an immunosuppressant that blocks the activation of T helper cells and interferes with the release of interleukin-2 and thereby prevents organ rejection in transplantation processes. Statins are produced by Monascus purpureus. Statins are competitive inhibitor of enzyme HMG CoA reductase, an enzyme of cholesterol biosynthesis.