Given above is the representation of a kind of chromosomal mutation. What is the kind of mutation represented?
A
Deletion
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B
Duplication
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C
Inversion
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D
Reciprocal translocation
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Solution
The correct option is A Inversion
Loss of one or more nucleotide bases in the DNA segment by removal of an intercalary DNA segment is known as deletion.
Duplication is the presence of an extrachromosomal segment which is attached to the normal homologous chromosome causing duplication of set of genes in the same chromosome.
Inversion is a chromosomal mutation where a segment of a chromosome is reversed end to end. It occurs by the introduction of break-in a single chromosome, its rotation by 180 degrees followed by its reinsertion in the same location.
Exchange of chromosomal segments between two non-homologous chromosomes is called reciprocal translocation.
In the given image, A"BCD”EFGH is mutated to A”DCB”EFGH which means that segment “BCD” is inverted to “DCB”. There is no duplication, deletion or exchange of segments but the intercalary segment “BCD” is rotated to 180 degrees.