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Insulin in Humans

Given figure ...

Question

Given figure represents the maturation of pro-insulin into insulin. Identify the product A.

A

Polypeptide chain A

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B

Polypeptide chain B

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C

Polypeptide chain C

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D

Both A and B

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Solution

The correct option is D Polypeptide chain C
There are three polypeptide chains (polypeptide A, B and C) in pro-insulin, which is the inactive form. It gets active after the removal of polypeptide C.
So, the answer is polypeptide C.

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Similar questions

Q. The given figure represents the maturation of proinsulin into insulin. Identify the product A. [1]

https://lh5.googleusercontent.com/58TAcvWL4W2Ma0ytxy1SFCK0u3Yx9JqjXXG0OdmqgSy5-JrkEsvjD4LAVkbq6ctn7BkCoh-SA9oGpAKmQEgCBfeCkgWnFPJL2BY4YgT0sas_6LHzhkY_MjlPazWpWaSVcZNnox7F

a. Polypeptide A
b. Polypeptide B
c. Polypeptide C
d. Both (b) and (c)

Q. Which of the following statements regarding the structure of proinsulin and mature insulin are not correct?
(i) Proinsulin is made up of three polypeptide chains A, B, and C.
(ii) C-polypeptide chain with 33 amino acids is removed prior to insulin formation.
(iii) Mature insulin is made up of 51 amino acids and arranged in two polypeptide chains-A and B.
(iv) Polypeptide chain A has 30 amino acids and polypeptide chain B has 21 amino acids.
(v) Polypeptide chains A and B are interconnected by only one S-S linkage.

Q. The structure of insulin consists of two polypeptide chains A and B. These two polypeptide chains have

Q. Total amino acids in insulin (bovine) are 51 in polypeptide chains A and B. How many amino acids are there in chain A?

Q. Assertion :Insulin is a globular protein. Reason: It has two polypeptide chains with 21 and 30 amino acids joined by sulphur bridges connecting cysteine amino acid on the two chains.

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