Question

Go through the following statements
(i) Failure of cytokinesis after telophase stage of cell division results in aneuploidy
(ii) In sickle cell anaemia, there is a single base substitution at the sixth codon of the beta globin gene from GAG to GCG.
(iii) In phenylketonuria, phenylalanine is accumulated and is converted to phenylpyruvic acid and other derivatives.
(iv) In sickle cell anaemia, the mutant hemoglobin molecule undergoes polymerization under low oxygen tension causing the change in the shape of RBC.
Find the out the correct statements,

• A. (i), (ii), & (iii)
• B. (ii), (ii), & (iv)
• C. (iii) & (iv)
• D. All are correct

Answer 1

The correct option is C (iii) & (iv)

Failure of cytokinesis after telophase results in polyploidy. In sickle cell anemia GAG is changed to GUG.