Question

High concentration of fluoride is poisonous and harmful to bone and teeth at levels over

• A. 1 ppm
• B. 3 ppm
• C. 5 ppm
• D. 10 ppm

Answer 1

The correct option is D

10 ppm

Early symptoms of acute fluoride poisoning include gastric pain, nausea, vomiting, and headaches. Fluoride-induced nephrotoxicity is dose-dependent, typically requiring serum fluoride levels exceeding 50 micromoles per liter (about 1 ppm) to cause clinically significant renal dysfunction.