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Question

High concentration of fluoride is poisonous and harmful to bone and teeth at levels over

A

1 ppm

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B

3 ppm

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C

5 ppm

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D

10 ppm

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Solution

The correct option is D
10 ppm

Early symptoms of acute fluoride poisoning include gastric pain, nausea, vomiting, and headaches. Fluoride-induced nephrotoxicity is dose-dependent, typically requiring serum fluoride levels exceeding 50 micromoles per liter (about 1 ppm) to cause clinically significant renal dysfunction.

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