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Nucleosome

Histones are ...

Question

Histones are responsible for packaging the DNA into a compact structure.

A

nucleotides

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B

proteins

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C

nucleic acids

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D

carbohydrates

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Solution

The correct option is B proteins
Histones are proteins that condense and package the DNA of a eukaryotic cell into units called nucleosomes. Their positive charge allows them to associate with the negatively charged DNA.

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Q. Assertion :Histones are basic proteins of major importance in packaging of eukaryotic DNA. DNA and histones comprise chromatin forming the bulk of eukaryotic chromosome. Reason: Histones are of five major types:

H_{1}, H_{2} A, H_{2} B, H_{3}

H_{4}

.

Q. DNA is packaged with non-histone protein to form nucleoid.

Q. Histone is a protein that primarily works as a DNA packaging molecule.

Q. How are the following formed and involved in DNA packaging in a nucleus of a cell?
(i) Histone octomer (ii) Nucleosome (iii) Chromatin.

Q. Go through the following statements
(i) A typical nucleosome contains 400 bp of DNA helix.
(ii) The positively charged DNA is wrapped around the negatively charged histone octamer to form a structure called nucleosome.
(iii) Histones are rich in the basic amino acid residues asparagine and valine
(iv) The packing of chromatin at higher level requires additional set of proteins that collectively are referred to as Non-histone chromosomal proteins.

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