Question

How are sticky ends formed on DNA strands? Why are they so called?

Answer 1

Restriction enzymes can cut the DNA at specific sequences called the recognition sites or restriction sites. Restriction digestion at certain sites leads to the formation of overhanging strands that are known as sticky ends. This happens as the DNA are cut at different regions. They are called so because they can form base pairs and bind to the complementary strands having a similar sticky end.