Question

How blood cloating in human being?

Answer 1

The coagulation cascade is a complex chemical process that uses 10 different proteins (called coagulation factors) found in plasma in the blood. Put simply, the clotting process changes blood from a liquid to a solid at the site of injury through given stages :

1. Injury - A small tear in a blood vessel wall causes bleeding.

2. Vessel constriction - To control blood loss the blood vessel narrows, thus limiting blood flow through the vessel.

3. Platelet plug - In response to the injury, cells in the blood called platelets are activated. The platelets stick to one another and to the wound site to form a plug. The protein von Willebrand factor (VWF) helps the platelets stick to each other and to the blood vessel wall.

4. Fibrin clot - Next, clotting factor proteins trigger production of fibrin, a strong, strand-like substance that forms a fibrin clot, a mesh-like net that keeps the plug firm and stable. Over the next several days to weeks, the clot strengthens and then dissolves as the wounded blood vessel wall heals.