Question

How do bioactive molecules of fungal origin help in restoring good health of humans?

Answer 1

Introduction:

Following are the bioactive molecules produced by fungi that help humans:-

● Cyclosporin A

● Statin

Cyclosporin:

Cyclosporin A, derived from the fungus Trichoderma polysporum, is used as an immunosuppressant during organ transplantation. These function by suppressing the immune system of the host, thereby preventing major immune response against foreign antibodies present on the transplanted graft.



Statin:

Statins are produced by the yeast, Monascus purpureus. Statin acts as a competitive inhibitor of the enzyme that catalyses the biosynthesis of cholesterol. As a result, statins help in lowering the blood cholesterol level.