Mutation:
- A mutation is a rapid, heritable alteration in an organism's genetic makeup or DNA sequence.
- Mutations can result through viral infection, errors in DNA replication during cell division, and exposure to mutagens.
- Either errors in DNA replication or environmental variables like UV light and cigarette smoke cause it to happen.
Mutation occurs due to the following causes:
- It is caused by any sudden change in the sequences of a gene due to which the variation gets duplicated and gets inherited in the subsequent generations.
- The change caused can be either an alteration of one nucleotide within the DNA or the deletion, or insertion, of a nucleotide, or the rearrangement of a larger length gene on chromosomes.
Internal Causes:
- It occurs when the DNA copies incorrectly during the replication cycle.
- This follows phenotypic changes.
- This occurs due to abnormal internal biological activities.
External Causes:
- Additionally, exposure to environmental elements including smoking, sunshine, and radiation can result in mutations.
- DNA breaks down when specific chemicals or radiation are employed to cause it to do so.
- UV exposure causes the thymine dimers (T-T) to break, altering the DNA.