A nerve impulse is an electrical signal that travels along an axon. There is an electrical difference between the inside of the axon and its surroundings, like a tiny battery. When the nerve is activated, there is a sudden change in the voltage across the wall of the axon, caused by the movement of ions in and out of the neuron. This triggers a wave of electrical activity that passes from the cell body along the length of the axon to the synapse.