Muscle contraction begins when the nervous system generates a signal. The signal, an impulse called an action potential, travels through a type of nerve cell called a motor neuron. The neuromuscular junction is the name of the place where the motor neuron reaches a muscle cell. Skeletal muscle tissue is composed of cells called muscle fibers. When the nervous system signal reaches the neuromuscular junction a chemical message is released by the motor neuron. The chemical message, a neurotransmitter called acetylcholine, binds to receptors on the outside of the muscle fiber. That starts a chemical reaction within the muscle.