Question

How do you activate B cells?

Answer 1

B cell activation:

1. B cells or B lymphocytes become activated when they come in contact with an antigen protein of a pathogen.
2. In most cases, an activated helper T cell stimulates the activation of the B cell.
3. Once an antigen triggers the activation of a T cell, it is able to activate a B cell that already recognizes the same antigen.
4. The activation is followed by a cell-cell interaction between the CD40 protein-ligand on the T cell surface and CD40 protein on the B cell surface.
5. Secretion of cytokinins by the helper T cell also stimulates the activation of the B cell.