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Question
How to compare the acidic strength by inductive and mesomeric effect?
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Solution
The mesomeric effect is given priority over Inductive effect when both effects come into play.
Inductive:
More -I (Negative inductive effect) - more acidic
More+I (Positive inductive effect) - less acidic
Mesomeric:
More -M or -R - more acidic.
More+M or +R - less acidic.
The mesomeric effect is given priority over Inductive effect when both effects come into play.
Inductive:
More -I (Negative inductive effect) - more acidic
More+I (Positive inductive effect) - less acidic
Mesomeric:
More -M or -R - more acidic.
More+M or +R - less acidic.
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