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Question

$I^{A}$ allele produces the trait ___ , while $I^{B}$ produces _ on human RBCs.

A

antigen A; antigen B

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B

antibody A; antibody B

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C

antibody B; antibody A

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D

antigen A; antigen A

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Solution

The correct option is A antigen A; antigen B
The alleles mentioned above are two of the three alleles involved in the control of ABO blood groups in humans. The $I^{A}$ allele produces a glycosyl transferase enzyme that adds the sugar α N-acetyl galactosamine to the polysaccharide to produce the A antigen on the surface of RBCs. The $I^{B}$ allele produces a different glycosyltransferase enzyme that adds the sugar galactose to produce the B antigen on the surface of RBCs.

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