Question

Identify the correct sequence of events occurring in eukaryotic transcription,
(A) Binding of RNA polymerase
(B) Phosphorylation of C-terminus domain
(C) Transcription initiation
(D) Binding of transcription factors

• A. A→B→D→C
• B. A→D→B→C
• C. D→A→B→C
• D. C→A→D→B

Answer 1

The correct option is C D→A→B→C

Transcription in eukaryotes is initiated with the help of transcription factors responsible for recognising the promoter to which the RNA polymerase binds, which determines the transcription start point. Once the initiation complex is assembled the C-terminus domain of the initiation complex is phosphorylated, which leads the polymerase to leave the pre-initiation complex and begin RNA synthesis.