Question

Identify the correct statement regarding enzyme inhibition.

• A. Non-competitive inhibition of an enzyme can be overcomed by adding large amount of substrate.
• B. Competitive inhibition is seen when a substrate competes with an enzyme for binding to an inhibitor protein.
• C. Competitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme.
• D. Non-competitive inhibitors often bind to the enzyme irreversibly.

Answer 1

The correct option is C Competitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme.

Competitive inhibition is the inhibition of an enzyme by an inhibitor which has structural similarity to the active site and thus competes with the substrate for binding with the active site. Competitive inhibition is a reversible inhibition and depends on the relative concentration of substrate and inhibitor.