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Question

Identify the wrong statement with reference to the gene ‘I’ that controls ABO blood groups.


A

When IA and IB are present together, they express the same type of sugar.

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B

Allele ‘i’ does not produce any sugar

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C

The gene (I) has three alleles.

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D

A person will have only two of the three alleles.

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Solution

The correct option is A

When IA and IB are present together, they express the same type of sugar.


The correct option is A:

Explanation of the correct option:

  1. The presence or absence of two surface antigens (chemicals that might trigger an immunological response) on RBCs, notably A and B, determines the ABO grouping.
  2. Two natural antibodies can be found in the plasma of different people (proteins produced in response to antigens).
  3. The gene I is in charge of ABO blood types. Sugar polymers protrude from the surface of the plasma membrane of red blood cells, and the kind of sugar is controlled by the gene.
  4. IA, IB, and i are the three alleles of the gene (I). Alleles IA and IB create a slightly different kind of sugar, whereas allele i produces no sugar at all.
  5. Each person has any two of the three I gene alleles since humans are diploid organisms. Over i IA and IB have complete dominance.
  6. When IA and i are both present, only IA expresses (since i do not create sugar), and when IB and i are both present, only IB expresses. However, due of co-dominance, when IA and IB are present together, they both express their own types of sugars.

Explanation of the incorrect option:

Option B:

IA, IB, and i are the three alleles of the gene (I). Alleles IA and IB create a slightly different kind of sugar, whereas allele i produces no sugar at all.

Option C:

IA, IB, and i are the three alleles of the gene (I). Alleles IA and IB create a slightly different kind of sugar, whereas allele i produces no sugar at all.

Option D:

Each person has any two of the three I gene alleles since humans are diploid organisms. Over i IA and IB have complete dominance.

Final answer: Due of co-dominance, when IA and IB are present together, they both express their own types of sugars.


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