Question

Identify the wrong statement with reference to the structure of human insulin :

• A. Insulin is synthesised as a pre-hormone which contains an extra stretch called C peptide.
• B. A and B chains are combined by disulphide bonds to form humulin.
• C. Human insulin is made up of 51 amino acids arranged in two polypeptide chains.
• D. In these, chain A is made up of 30 amino acids and chain B is made up of 21 amino acids.

Answer 1

The correct option is D In these, chain A is made up of 30 amino acids and chain B is made up of 21 amino acids.

Human insulin is made up of 51 amino acids arranged in two polypeptide chains: A, having 21 amino acids and B, with 30 amino acids. The two polypeptide chains are interconnected by two disulphide bridges. The two polypeptide chains are interconnected by two disulphide briges. The hormone develops from a storage product called pronsulin. Proinsulin has three chains: A, B and C, C-chain with 33 amino acids is removed prior to insulin formation.

So, the correct option is 'D'.