Question

Identify the wrong statement with reference to transport of oxygen.

• A. Higher H⁺ conc. in alveoli favours the formation of oxyhaemoglobin
• B. Low pCO₂ in alveoli favours the formation of oxyhaemoglobin
• C. Binding of oxygen with haemoglobin is mainly related to partial pressure of O₂
• D. Partial pressure of CO₂ can interfere with O₂ binding with haemoglobin

Answer 1

The correct option is A

Higher H⁺ conc. in alveoli favours the formation of oxyhaemoglobin

The correct option is A:

Explanation of the correct option:

1. RBCs contain haemoglobin, a red-colored iron-containing pigment.
2. O₂ can attach to haemoglobin and generate oxyhaemoglobin in a reversible manner.
3. The partial pressure of O₂ is the most important factor in oxygen binding to haemoglobin. Other factors that can interfere with this binding include CO₂ partial pressure, hydrogen ion concentration, and temperature.
4. The parameters are all favourable for the synthesis of oxyhaemoglobin in the alveoli, which have a high pO₂, low pCO₂, reduced H⁺ content, and lower temperature.
5. The circumstances for dissociation of oxygen from oxyhaemoglobin are favourable in tissues with low pO2, high pCO2, high H+ content, and higher temperature.

Explanation of the incorrect option:

Option B:

The parameters are all favourable for the synthesis of oxyhaemoglobin in the alveoli, which have a high pO₂, low pCO₂, reduced H⁺ content, and lower temperature.

Option C:

The partial pressure of O₂ is the most important factor in oxygen binding to haemoglobin. Other factors that can interfere with this binding include CO₂ partial pressure, hydrogen ion concentration, and temperature.

Option D:

The partial pressure of O₂ is the most important factor in oxygen binding to haemoglobin. Other factors that can interfere with this binding include CO₂ partial pressure, hydrogen ion concentration, and temperature.

Final answer: Lower concentration of H+ ion in alveoli favours the formation of oxyhaemoglobin.