Question

Identify the wrong statement with reference to transport of oxygen.

• A. Higher $H^{+}$ conc. in alveoli favours the formation of oxyhaemoglobin
• B. Low $pC{O}_2$ in alveoli favours the formation of oxyhaemoglobin
• C. Binding of oxygen with haemoglobin is mainly related to partial pressure of $O_2$
• D. High partial pressure of $C{O}_2$ can interfere with $O_2$ binding with haemoglobin.

Answer 1

The correct option is A Higher $H^{+}$ conc. in alveoli favours the formation of oxyhaemoglobin

The oxygen dissociation curve is highly useful in studying the effect of factors like $pC{O}_2,H^{+}$ concentration, etc., on binding of $O_2$ with haemoglobin. In the alveoli, where there is high $p{O}_2$ , low $pC{O}_2$ , lesser $H^{+}$ concentration and lower temperature, the factors are all favourable for the formation of oxyhaemoglobin.
In the tissues, where low $p{O}_2$ , high $pC{O}_2$ , high $H^{+}$ concentration and higher temperature exist, the conditions are favourable for dissociation of oxygen from the oxyhaemoglobin.