If a segment of mRNA molecule has the sequence 5' GUACCGAUCG 3', which of the following could have been the template DNA molecule?
A
5' GCUAGCCAUG 3'
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B
5' GUACCGAUCG 3'
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C
3' CATGGCTAGC 5'
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D
3' CGATCGGTAC 5'
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Solution
The correct option is B 3' CATGGCTAGC 5' Pairing of strands follows pairing principle. That is A pairs with T; whereas C pairs with G.
One strand of DNA holds the information that codes for various genes; this strand is often called the template strand or antisense strand (containing anticodons). The other, and complementary, strand is called the coding strand or sense strand (containing codons). Since mRNA is made from the template strand, it has the same information as the coding strand.