Question

If both parents are carriers for thalassemia, which is an autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child?

• A. 100%
• B. 25%
• C. 50%
• D. No chance

Answer 1

The correct option is B

25%

The correct option is B.

The explanation for the correct option:

1. Our bodies have less hemoglobin than usual due to the genetic blood condition thalassemia.
2. Oxygen can be carried by red blood cells thanks to hemoglobin.
3. We may become weary from the anemia brought on by thalassemia.
4. Two altered genes (mutations), one from each parent, are inherited to have an autosomal recessive condition.
5. Usually, two carriers pass on these diseases.
6. They have one modified gene (recessive gene) and one unaffected gene (dominant gene) for the disorder, yet their health is rarely affected.
7. The-and-globin gene clusters on chromosomes 16 and 11, respectively, are mutated in thalassemia, a hereditary autosomal recessive illness.
8. There are two primary forms of it: thalassemia and anemia.
9. It is characterized by the absence or diminished synthesis of globin chains of hemoglobin (1, 2).
10. For a child to be impacted by the condition, they must inherit one faulty gene from each of their parents.
11. A child of two carriers of an autosomal recessive disorder has a 25% chance of developing the ailment and a 50% chance of developing carriers who appear normal.

Final answer: If both parents are carriers of thalassemia, which is an autosomal recessive disorder, there is a 25% chance of a pregnancy resulting in an affected child.