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Question

If both parents are carriers for thalassemia, which is an autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child?

A
No chance
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B
50%
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C
25%
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D
100%
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Solution

The correct option is C 25%
An autosomal recessive disorder means two copies of an abnormal gene must be present in order for the disease or trait to develop. Cystic Fibrosis, Sickle Cell Anemia, Tay-Sachs Disease, thalassemia are some of the examples of such inheritance.
If both parents are carriers for the autosomal recessive disorder thalassemia, there is a 25% chance that the resulting child is affected.

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